Dipl. Pharm. Paul Robert Neumann
Pharmazeutische Technologie und Biopharmazie
Arbeitsgruppe Biopharmazie
Raum 420.2
Kurt-Mothes-Straße 3
06120 Halle (Saale)
Telephone: +49 (0) 345 55-25148
E-mail: paul.neumann@pharmazie.uni-halle.de
Research Projects
My aim is to apply polymers and nanotechnology concepts in order to make a contribution to the development of effective nanomedicines for diagnosis and treatment. I am working on biocompatible, biodegradable conjugated polymer nanoparticles for in vivo imaging applications.
In the future, the development of these intravesical diagnostic nanoparticles could enhance visualisation during surgical resection.
Curriculum vitae
01/2018 – 03/2018 - research stay at Stanford University in the research group of Prof. Jianghong Rao http://raolab.stanford.edu/
since 05/2018 advanced training of the Federal Association of German Pharmacist as a specialist pharmacist for pharmaceutical technology
since 07/2016 - Ph.D. student in the working group of Prof. Lea Ann Dailey
05/2015 – 10/2015 - King´s College London, Pharmaceutical Innovation. Department of Pharmacy & Forensic Science and Gamlen Tableting Ltd. - Diploma Thesis "Factorial evaluation of a blending model. Impact on tablet critical quality attributes"
09/2012 – 01/2013 - University of Basel, Department of Pharmaceutical Sciences - Semester abroad in Pharmaceutical Sciences
10/2010 – 03/2015 - University of Leipzig
Pharmaceutical Sciences
Teaching
- Seminar for 3. semester students about semisolid dosage forms
- Supervision of the practical course about semisolid dosage forms
- Seminar for 7. semester about biopharmaceutical concepts
- Supervision of practical course about solid dosage forms
Conference contributions
Optical imaging with borylated polyfluorene nanoparticles. Particle Based Materials Symposium, September 2019, Ulm - poster (awarded with poster prize)
Optical imaging with borylated polyfluorene nanoparticles. BioNanoMed, April 2019, Graz - oral presentation
A new optical imaging probe - bright and almost unbleachable Controlled Release Society Local Chapter Meeting, March 2019, Leipzig, Germany - poster
Borylated polyfluorenes are highly stable optical imaging probes. Molecular Imaging Symposium, MoBi. December 2018 at Max-Planck-Institute for Experimental Medicine, Göttingen - poster
Biodegradation of PEG-PLGA-based nanodiagnostics containing π-conjugated polymers as optical imaging agents. April 2017 - Journal of Interdisciplinary Nanomedicine, John Wiley & Sons, Ltd. European Conference on Nanomedicine at King´s College London, 2017 - poster
Publications
Different PEG‐PLGA Matrices Influence In Vivo Optical/Photoacoustic Imaging Performance and Biodistribution of NIR‐Emitting π ‐Conjugated Polymer Contrast Agents. Aug. 2020 - Advanced Healthcare Materials https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.202001089
In vitro and in vivo antitubercular activity of benzothiazinone-loaded human serum albumin nanocarriers designed for inhalation. Aug. 2020 - Journal of Controlled Release https://www.sciencedirect.com/science/article/abs/pii/S0168365920304624
Enhanced optical imaging properties of lipid nanocapsules as vehicles for fluorescent conjugated polymers. Jul. 2020 - European Journal of Pharmaceutics and Biopharmaceutics https://www.sciencedirect.com/science/article/pii/S0939641120302204
In vivo optical performance of a new class of near infrared-emitting conjugated polymers: borylated PF8-BT. Nov. 2019 - ACS Applied Materials & Interfaces https://pubs.acs.org/doi/abs/10.1021/acsami.9b17022
Low molecular weight PEG–PLGA polymers provide a superior matrix for conjugated polymer nanoparticles in terms of physicochemical properties, biocompatibility and optical/photoacoustic performance. Jul. 2019 - Journal of Materials Chemistry B https://pubs.rsc.org/en/content/articlelanding/2019/tb/c9tb00937j#!divAbstract
Post-Polymerization C-H Borylation of Donor-Acceptor Materials Gives Highly Efficient Solid State Near-Infrared Emitters for NIR-OLEDs and Effective Biological Imaging. Aug 2017 - ACS Applied Materials & Interfaces https://pubs.acs.org/doi/abs/10.1021/acsami.7b08473